Dr. Robert E. Rhoads' Publications

Jemielity, J., Fowler, T., Zuberek, J., Stepinski, J., Lewdorowicz, M., Niedzwiecka, A., Stolarski, R., Darzynkiewicz, E., and Rhoads R. E. (2003) Novel ‘Anti-Reverse’ cap analogues with superior translational properties. RNA 9, 1108-1122

Zhao, X., Lamphear, B. J. Xiong, D., Knowlton, K., and Rhoads R. E. (2003) Protection of cap-dependent protein synthesis in vivo and in vitro with an eIF4G-1 variant highly resistant to cleavage by Coxsackievirus 2A protease. J. Biol. Chem. 278, 4449-4457

Stachelska, A., Wieczorek, Z., Ruszczynska, K., Stolarski, R., Pietrzak, M., Lamphear, B. J., Rhoads R. E., Darzynkiewicz, E., and Jankowska-Anyszka, M. (2002) Interaction of three Caenorhabditis elegans isoforms of translation initiation factor eIF4E with mono- and trimethylated mRNA 5’ cap analogues. Acta Biochimica Polonica 49, 671-682

Miyoshi, H., Dwyer, D. S., Keiper, B. D., Jankowska-Anyszka, M., Darzynkiewicz, E., and Rhoads, R. E. (2002) Discrimination between mono- and trimethylated cap structures by two isoforms of C. elegans eIF4E. EMBO J.21, 4680 – 4690

Bradley, C. A., Padovan, J. C., Thompson, T. L., Benoit, C. A., Chait, B. T. , and Rhoads R. E. (2002) Mass spectrometric analysis of the N-terminus of translational initiation factor eIF4G-1 reveals novel isoforms. J. Biol. Chem.277,

Amiri, A., Keiper, B. D., Kawasaki , I. , Fan, Y., Kohara, Y., Rhoads, R. E, and Strome, S. (2001) An isoform of eIF4E is a component of germ granules and is required for spermatogenesis in C. elegans.Development 128 , 3899-3912

Stepinski, J., Waddell, C., Stolarski, R., Darzynkiewicz, E., and Rhoads, R. E. (2001) Synthesis and properties of mRNAs containing the novel “anti-reverse” cap analogues 7-methyl(3’-O-methyl)GpppG and 7-methyl(3’-deoxy)GpppG. RNA7, 1486-1495

Korneeva, N. L., Lamphear, B. J., Hennigan, F. L. C., Merrick, W. C. and Rhoads, R. E., (2001) Characterization of the two eIF4A binding sites on human eIF4G-1. J. Biol. Chem. 276, 2872-2879

Korneeva, N. L., Lamphear, B. J., Hennigan, F. L. C., and Rhoads, R. E. (2000) Mutually cooperative binding of eIF3 and eIF4A to human eIF4G-1. J. Biol. Chem. 275,

Badorff, C., Fichtlscherer, B., Rhoads, R. E., Zeiher, A. M., Muelsch, A., Dimmeler, S., and Knowlton, K. U. (2000) Nitric oxide inhibits dystrophin proteolysis by Coxsackieviral protease 2A through S-nitrosylation: a protective mechanism against enteroviral cardiomyopathy. Circulation102, 2276-2281

Badorff, C., Berkely, N., Mehrotra, S., Talhouk, J. W., Rhoads, R. E., and Knowlton, K. U. (2000) Enteroviral protease 2A directly cleaves dystrophin and is inhibited by a dystrophin-based substrate analogue. J. Biol. Chem. 275 ,

Keiper, B. D., Lamphear, B. J., Deshpande, A. M., Jankowska-Anyszka, M., Aamodt, E. J., Blumenthal, T., and Rhoads, R. E. (2000) Functional characterization of five eIF4E isoforms in Caenorhabditis elegans. J. Biol. Chem . 275,

Badorff, C., Lee, G.-H., Lamphear, B. J., Martone, M.. E., Campbell, K. P., Rhoads, R. E., and Knowlton, K. U. (1999) Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nature Medicine5, 320-326

Cai, A., Jankowska-Anyszka, M., Centers, A., Chlebicka, L., Stepinski, J., Stolarski, R., Darzynkiewicz, E., and Rhoads, R. E. (1999) Quantitative assessment of mRNA cap analogs as inhibitors of in vitro translation. Biochemistry38, 8538-8547

Good, D., Schwarzenberger, P., Eastham, J., Rhoads, R., Hunt, J., Collins, M., Batzer, M., Theodossiou, C., Kolls, J., and Grimes, S. (1999) Cloning and characterization of the prostate- specific membrane antigen promoter. J. Cell. Biochem.74, 395-405

Myers, M. G., Jr., Mendez, R, Shi, P., Pierce, J. H., Rhoads, R., and White, M. F. (1998) The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling. J. Biol. Chem.273,

Keiper, B. D., and Rhoads, R. E. (1999) Translational recruitment of Xenopus maternal mRNAs in response to poly(A) elongation requires initiation factor eIF4G-1. Dev. Biol. 206, 1-14

Kerekatte, V., Keiper, B. D., Badorff, C., Cai, A., Knowlton, K. U., and Rhoads, R. E. (1999) Cleavage of poly(A)-binding protein by coxsackieviral 2A protease in vitro and in vivo: another mechanism for host protein synthesis shut-off? J. Virol. 73, 709-717

Bovee, M. L., Lamphear, B. J., Rhoads, R. E., and Lloyd, R. E. (1998) Direct cleavage of eIF4G by poliovirus 2A protease is inefficient in vitro. J. Virol. 245, 241-249

Jankowska-Anyszka, M., Lamphear, B. J., Aamodt, E. J., Harrington, T., Darzynkiewicz, E., Stolarski, R., and Rhoads R. E. (1998) Multiple isoforms of eukaryotic protein synthesis initiation factor 4E in C. elegans can distinguish between mono- and trimethylated mRNA cap structures. J. Biol. Chem. 273,

Gan, W., La Celle, M., and Rhoads, R. E. (1998) Functional characteriztion of the internal ribosome entry site of eIF4G mRNA. J. Biol. Chem. 273, 5006-5012

Gao, M..-X., Rychlik, W., and Rhoads, R. E. (1998) Cloning and characterization of human eIF4E genes. J. Biol. Chem. 273, 4622-4628

Sorrels, D., Black, D. R., Meschonat, C., Rhoads, R. E., De Benedetti, A., Gao, M., and Li, B. D. L. (1997) Competitive PCR to detect eIF4E gene amplification in breast cancer. Ann. Surg. Oncol. 5, 232-237.

Mendez, R., Kollmorgen, G., White, M. F., and Rhoads, R. E. (1997) Requirement of protein kinase C z for stimulation of protein synthesis by insulin. Mol. Cell. Biol. 17, 5184-5192

Borman, A. M., Kirchweger, R., Ziegler, E., Rhoads, R. E., Skern, T., and Kean, K. M. (1997) eIF4G and its proteolytic cleavage products: Effect on initiation of protein synthesis from capped, uncapped and IRES-containing mRNAs. RNA3, 186-196

Keiper, B. D., and Rhoads, R. E. (1997) Cap-independent translation initiation in Xenopus oocytes. Nucl. Acids Res. 25, 395-402

Lamphear, B. J., and Rhoads, R. E. (1996) A single amino acid change in protein synthesis initiation factor 4G renders cap-dependent translation resistant to picornaviral 2A proteases. Biochemistry35,

Mendez, R., Myers, M. G., Jr., White, M. F., and Rhoads, R. E. (1996) Stimulation of protein synthesis, eIF4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate-1 and phosphatidylinositol-3-kinase. Mol. Cell. Biol. 16, 2857-2864

Gan, W. and Rhoads, R. E. (1996) Internal initiation of translation directed by the 5’-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation. J. Biol. Chem.271, 623-626

Lamphear, B. J., Kirchweger, R., Skern, T. and Rhoads, R. E. (1995) Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G with picornaviral proteases. Implications for cap-dependent and cap-independent translational initiation. J. Biol. Chem. 270,

Joshi, B., Cai, A.-L., Keiper, B., Minich, W. B., Mendez, R., Beach, C. M., Stepinski, J., Stolarski, R., Darzynkiewicz, E. and Rhoads, R. E. (1995) Phosphorylation of eukaryotic protein synthesis initiation factor 4E at Ser-209. J. Biol. Chem. 270,

Yan, R., and Rhoads, R. E. (1995) Human protein synthesis initiation factor eIF-4 g is encoded by a single gene (EIF4G) that maps to chromosome 3q27-qter. Genomics26, 394-398

Joshi, B., Morley, S. J., Rhoads, R. E., and Pain, V. M. (1995) Inhibition of protein synthesis by the heme-controlled eIF-2 a kinase leads to the appearance of mRNA-containing 48S complexes that contain eIF-4E but lack methionyl-tRNA f.. Eur. J. Biochem. 228, 31-38

Stepinski, J., Bretner, M., Jankowska, M., Felczak, K., Stolarski, R., Wieczorek, Z., Cai, A.-L., Rhoads, R. E., Temeriusz, A., Haber, D., and Darzynkiewicz, E. (1995) Synthesis and properties of p1, p2-, p1,p3- and p1,p4-dinucleoside di-, tri- and tetraphosphate mRNA 5’-cap analogues. Nucleosides & Nucleotides14, 717-721

Minich, W. B., Balasta, M. L., Goss, D. J., and Rhoads, R. E. (1994) Chromatographic resolution of invivo-phosphorylated and nonphosphorylated translation initiation factor eIF-4E, Demonstration of increased cap affinity of the phosphorylated form. Proc. Natl. Acad. Sci. USA 91, 7668-7672

Kirchweger, R., Ziegler, E., Lamphear, B. J., Waters, D., Liebig, H.-D., Sommergruber, W., Sobrino, F., Hohenadl, C., Blaas, D., Rhoads, R. E. and Skern, T. (1994) Foot-and-mouth disease virus leader proteinase: Purification of the Lb form and determination of its cleavage site on eIF-4 g. J. Virol. 68, 5677-5684

Barve, S. S., Cohen, D. A., De Benedetti, A., Rhoads, R. E., and Kaplan, A. M. (1994) Mechanism of differential regulation of IL-2 murine Th1 and Th2 T cell subsets. J. Immunol. 152, 1171-1181

Jagus, R., Huang, W. I., Hiremath, L. S., Stern, B. D., and Rhoads, R. E. (1993) Mechanism of action of developmentally regulated sea urchin inhibitor of eIF4. Dev. Genet. 14, 412-423

Joshi, B., Yan, R. and Rhoads, R. E.(1994) In vitro synthesis of human protein synthesis initiation factor eIF-4 g and its localization on 43S and 48S initiation complexes. J. Biol. Chem.269, 2048-2055

Rinker-Schaeffer, C. W., Graff, J. R., De Benedetti, A., Zimmer, S. G. and Rhoads, R. E. (1993) Decreasing the level of translation initiation factor 4E with antisense RNA causes reversal of ras-mediated transformation and tumorigenesis of cloned rat embryo fibroblasts. Int. J. Cancer55, 841-847

Lamphear, B. J., Yan, R., Yang, F., Waters, D., Liebig, H.-D., Klump, H., Kuechler, E., Skern, T., and Rhoads, R. E. (1993) Mapping the cleavage site in protein synthesis initiation factor eIF-4 g of the 2A proteases from human coxsackievirus and rhinovirus. J. Biol. Chem. 268,

Liebig, H.-D., Ziegler, E., Yan, R., Hartmuth, K., Klump, H., Kowalski, H., Blaas, D., Sommergruber, W., Frasel, L., Lamphear, B., Rhoads, R. E., Kuechler, E., and Skern, T. (1993) Purification of Two Picornaviral 2A Proteinases: Interaction with eIF-4 g and influence on in vitro translation. Biochemistry32, 7581-7588

Rychlik, W., and Rhoads, R.E.(1992) Nucleotide sequence of rabbit eIF-4E cDNA. Nucl. Acids Res. 20, 6415

Allen, M. L., Metz, A. M., Timmer, R. T., Rhoads, R. E., and Browning, K.S.(1992) Isolation and sequence of the cDNAs encoding the subunits of the isozyme form of wheat protein synthesis initiation factor 4F. J. Biol. Chem.267,

Carberry, S. E., Friedland, D. E., Rhoads, R. E., and Goss, D. J. (1992) Binding of protein synthesis initiation factor 4E to oligoribonucleotides: Effects of cap accessibility and secondary structure. Biochemistry 31, 1427-1432

Yan, R., Rychlik, W., Etchison, D., and Rhoads, R. E.(1992) Amino acid sequence of the human protein synthesis initiation factor eIF-4 g. J. Biol. Chem. 267,

Joshi-Barve, S., De Benedetti, A., and Rhoads, R. E. (1992) Preferential translation of heat shock mRNAs in HeLa cells deficient in protein synthesis initiation factors eIF-4E and eIF-4 g. J. Biol. Chem. 267,

Rinker-Schaeffer, C. W., Austin, V., Zimmer, S., and Rhoads, R. E. (1992) ras-Transformation of cloned rat embryo fibroblasts results in increased rates of protein synthesis and eIF-4E phosphorylation. J. Biol. Chem. 267,

Brandt, P., Neve, R. L., Kammesheidt, A., Rhoads, R. E., and Vanaman, T. C. (1992) Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels. J. Biol. Chem. 267, 4376-4385

Joshi, B., and Joshi-Barve, S., Rhoads, R. E., and Pain, V. M. (1991) 40S Ribosomal complexes in reticulocyte lysates treated with the haem-controlled eIF-2 a kinase. Biochem. Soc. Trans. 19, 282S

Mavankal, G., and Rhoads, R. E. (1991) In vitro cleavage at or near the N-terminus of the helper component protein in the tobacco vein mottling virus polyprotein. Virology185, 721-731

De Benedetti, A., Joshi-Barve, S., Rinker-Schaeffer, C., and Rhoads, R. E. (1991) Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F. Mol. Cell. Biol. 11, 5435-5445

De Benedetti, A., and Rhoads, R. E. (1991) A novel BK virus-based episomal vector for expression of foreign genes in mammalian cells. Nucl. AcidsRes. 19, 1925-1931

Murphy, J. F., Rychlik, W., Rhoads, R. E., Hunt, A. G., and Shaw, J. G. (1991) A tyrosine residue in the small nuclear inclusion protein links the tobacco vein mottling virus VPg to the viral RNA. J. Virol. 65, 511-513

Luciano, C. S., Murphy, J. F., Rhoads, R. E., and Shaw, J. G. (1991) VPg-mediated aggregation of potyviral RNA. J. Gen. Virol. 72, 205-208

Manzella, J. M., Rychlik, W., Rhoads, R. E. (1991) Hershey, J.W.B., and Blackshear, P.J., Insulin induction of ornithine decarboxylase. J. Biol. Chem. 266, 2383-2389

Goss, D. J., Carberry, S. E., Dever, T. E., Merrick, W. C., and Rhoads, R. E. (1990) A fluorescence study of the interaction of protein synthesis initiation factors 4A, 4E and 4F with mRNA and oligonucleotide. Biochim. Biophys. Acta 1050, 163-166

Rychlik, W., Spencer, W. J., and Rhoads, R. E. (1990) Optimization of the annealing temperature for DNA amplification invitro. Nucl. AcidsRes. 18, 6409-6412

De Benedetti, A., and Rhoads, R. E. (1990) Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology. Proc. Natl. Acad. Sci. USA87, 8212-8216

Rychlik, W., Rush, J. S., Rhoads, R. E., and Waechter, C. J. (1990) Increased rate of phosphorylation-dephosphorylation of the translational initiation factor eIF-4E correlates with the induction of protein and glycoprotein biosynthesis in activated B lymphocytes. J. Biol. Chem. 265,

Goss, D. J., Carberry, S. E., Dever, T. E., Merrick, W. C., and Rhoads, R. E. (1990) A fluorescence study of the binding of m 7GpppG and rabbit globin mRNA to protein synthesis initiation factors 4A, 4E and 4F. Biochemistry29, 5008-5012

Tuazon, P. T., Morley, S. J., Dever, T. E., Merrick, W. C., Rhoads, R. E., and Traugh, J. A. (1990) Association of initiation factor eIF-4E in cap binding protein complex (eIF-4F) is critical for and enhances phosphorylation by protein kinase C. J. Biol. Chem. 265,

Carberry, S. E., Darzynkiewicz, E., Stepinski, J., Tahara, S. M., Rhoads, R. E., and Goss, D. J. (1990) A spectroscopic study of the binding of N-7-substituted cap analogs to human protein synthesis initiation factor 4E. Biochemistry29, 3337-3341

Chavan, A. J., Rychlik, W., Blaas, D., Kuechler, E., Watt, D. S., and Rhoads, R. E. (1990) Phenyl azide substituted and benzophenone-substituted phosphonamides of 7-methylguanosine 5'-triphosphate as photoaffinity probes for protein synthesis initiation factor eIF-4E and a proteolytic fragment containing the cap-binding site. Biochemistry29, 5521-5529

Kaspar, R. L., Rychlik, W., White, M. W., Rhoads, R. E., and Morris, D. R. (1990) Simultaneous cytoplasmic redistribution of ribosomal protein L32 mRNA and phosphorylation of eukaryotic initiation factor 4E after mitogenic stimulation of Swiss 3T3 cells. J. Biol. Chem. 265, 3619-3622

Murphy, J. F., Rhoads, R. E., Hunt, A. G., and Shaw, J. G. (1990) The VPg of tobacco etch virus is the 49-kDa proteinase or the N-terminal 24-kDa part of the proteinase. Virology, 178, 285-288

Joshi-Barve, S., Rychlik, W., and Rhoads, R. E. (1990) Alteration of the major phosphorylation site of eukaryotic protein synthesis initiation factor 4E prevents its association with the 48S initiation complex. J. Biol. Chem. 265, 2979-2983

Rychlik, W., and Rhoads, R. E. (1989) A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and invitro amplification of DNA. Nucl. AcidsRes. 17, 8543-8551

Carberry, S. E., Rhoads, R. E., and Goss, D. J. (1989) A spectroscopic study of the binding of m 7GTP and m 7GpppG to human protein synthesis initiation factor 4E. Biochemistry28, 8078-8083

Graybosch, R., Hellmann, G., Shaw, J. G., Rhoads, R. E., Hunt, A. G. (1989) Expression of a potyvirus non-structural protein in transgenic tobacco. Biochem. Biophys. Res. Commun. 160, 425-432

Domier, L. L., Franklin, K. M., Hunt, A. G., Rhoads, R. E., and Shaw, J. G. (1989) Infectious invitro transcripts from cloned cDNA of the potyvirus, tobacco vein mottling virus. Proc. Natl. Acad. Sci. USA86, 3509-3513

Hiremath, L. S., Hiremath, S. T., Rychlik, W., Joshi, S., Domier, L. L., and Rhoads, R. E. (1989) Invitro synthesis, phosphorylation and localization on 48S initiation complexes of human protein synthesis initiation factor 4E. J. Biol. Chem. 264, 1132-1138

Doebler, J. A., Rhoads, R. E., Anthony, A., and Markesbery, W. R. (1989) Neuronal RNA in Pick's and Alzheimer's diseases. Comparison of Disease-Susceptible and Disease-Resistant Cortical Areas. Arch. Neurol. 46, 134-137

Shahabuddin, M., Shaw, J. G., and Rhoads, R. E. (1988) Mapping of the tobacco vein mottling virus VPg cistron. Virology163, 635-637

Hiremath, S., Nuss, D., Ghabrial, S. A., and Rhoads, R. E. (1988) Molecular cloning of hypovirulence-associated double-stranded RNA in Endothiaparasitica and detection of sequence-related single-stranded RNA. J. Gen. Virol. 69, 2441-2453

Brandt, P., Zurini, M., Neve, R. L., Rhoads, R. E., and Vanaman, T. C. (1988) A C-terminal, calmodulin-like regulatory domain from the plasma membrane Ca 2+-pumping ATPase. Proc. Natl. Acad. Sci. USA85, 2914-2918

Hellmann, G. M., Shaw, J. G., and Rhoads, R. E. (1988) Invitro analysis of tobacco vein mottling virus NI a cistron: evidence for a virus-encoded protease. Virology163, 554-562

Jones, G., Hiremath, S. T., Hellmann, G. M., and Rhoads, R. E. (1988) Juvenile hormone regulation of mRNA levels for a highly abundant hemolymph protein in larval Trichoplusiani. J. Biol. Chem. 263, 1089-1092

Doebler, J. A., Markesbery, W. R., Anthony, A., Scheff, S. W., and Rhoads, R. E. (1988) Astrocyte RNA in relation to neuronal RNA depletion in Alzheimer's disease. ActaNeuropathol. (Berl)75, 272-276

Doebler, J. A., Markesbery, W. R., Anthony, A., Davies, R., Scheff, S. W., and Rhoads, R. E. (1988) Neuronal RNA in Relation to Alz-50 Immunoreactivity in Alzheimer's Disease. AnnalsofNeurology23, 20-24

Rychlik, W., Russ, M. A., and Rhoads, R. E. (1987) Phosphorylation Site of Eucaryotic Initiation Factor 4E. J. Biol. Chem. 262,

Luciano, C. S., Rhoads, R. E., and Shaw, J. G. (1987) Synthesis of potyviral RNA and proteins in tobacco mesophyll protoplasts inoculated by electroporation. PlantScience51, 295-303

Domier, L. L., Shaw, J. G., and Rhoads, R. E. (1987) Potyviral proteins share amino acid sequence homology with picorna-, como- and caulimoviral proteins. Virology158, 20-27

Rychlik, W., Domier, L. L., Gardner, P. R., Hellmann, G. M., and Rhoads, R. E. (1987) Amino acid sequence of the mRNA cap-binding protein from human tissues. Proc. Natl. Acad. Sci. USA84, 945-949

Doebler, J. A., Markesbery, W. R., Anthony, A., and Rhoads, R. E. (1987) In situ analysis of neostriatal RNA and chromatin in Alzheimer's disease. Neurology37, 309-313

Doebler, J. A., Markesbery, W. R., Anthony, A., and Rhoads, R. E. (1987) Neuronal RNA in relation to neuronal loss and neurofibrillary pathology in the hippocampus in Alzheimer's disease. J. Neuropath. Exptl. Neurol. 46, 28-39

Hiremath, S. T., L'Hostis, B., Ghabrial, S. A., and Rhoads, R. E. (1986) Terminal Structure of hypovirulence-associated dsRNAs in the chestnut blight fungus Endothiaparasitica. Nucl. AcidsRes. 14, 9877-9896

Domier, L. L., Franklin, K. M., Shahabuddin, M., Hellmann, G. M., Overmeyer, J. H., Hiremath, S. T., Siaw, M. F. E., Lomonossoff, G. P., Shaw, J. G., and Rhoads, R. E. (1986) The nucleotide sequence of tobacco vein mottling virus RNA. Nucl. AcidsRes. 14, 5417-5430

Hellmann, G. M., Hiremath, S. T., Shaw, J. G., and Rhoads, R. E. (1986) Cistron mapping of tobacco vein mottling virus. Virology151, 159-171

Rychlik, W., Gardner, P. R., Vanaman, T. C., and Rhoads, R. E. (1986) Structural analysis of the messenger RNA cap-binding protein. Presence of phosphate, suflhydryl and disulfide groups. J. Biol. Chem. 261, 71-75

Hiremath, L. S., Webb, N. R., and Rhoads, R.E. (1985) Immunological detection of the messenger RNA cap-binding protein. J. Biol. Chem. 260, 7843-7849

Thornbury, D. W., Hellmann, G. M., Rhoads, R. E., and Pirone, T. P. (1985) Purification and characterization of potyvirus helper component. Virology144, 260-267

Hellmann, G. M., Shaw, J. G., and Rhoads, R. E. (1985) On the origin of the helper component of tobacco vein mottling virus: Translational initiation near the 5' terminus of the viral RNA and termination by UAG codons. Virology143, 23-34

Siaw, M. F. E., Shahabuddin, M., Ballard, S., Shaw, J. G., and Rhoads, R. E. (1985) Identification of a protein covalently linked to the 5' terminus of tobacco vein mottling virus RNA. Virology142, 134-143

L'Hostis, B., Hiremath, S. T., Rhoads, R. E., and Ghabrial, S. A. (1985) Lack of sequence homology between double-stranded RNA from European and American hypovirulent strains of Endothiaparasitica. J. Gen. Virol. 66, 351-355

Xu, Z., Luciano, C. S., Ballard, S. T., Rhoads, R. E., and Shaw, J. G. (1984) Infection of tobacco protoplasts with liposome-encapsulated potyviral RNA. PlantScienceLetters36, 137-142

Webb, N. R., Chari, R. V. J., dePillis, G., Kozarich, J. W., and Rhoads, R. E. (1984) Purification of the messenger RNA cap-binding protein using a new affinity medium. Biochemistry23, 177-181

Rhoads, R. E., Hellmann, G. M., Remy, P., and Ebel, J. P. (1983) Translational recognition of messenger RNA caps as a function of pH. Biochemistry22, 6084-6088

Eschenfeldt, W. H., Cohen, B. G., and Rhoads, R. E. (1983) Structure of the 5'-terminus of hen oviduct lysozyme messenger ribonucleic acid. J. Biol. Chem. 258,

Hellmann, G. M., Shahabuddin, M., Shaw, J. G., and Rhoads, R. E. (1983) Molecular cloning of DNA complementary to tobacco vein mottling virus RNA. Virology128, 210-220

Hellmann, G. M., Thornbury, D. W., Hiebert, E., Shaw, J. G., Pirone, T. P., and Rhoads, R. E. (1983) Cell-free translation of tobacco vein mottling virus RNA. II. Immunoprecipitation of products by antisera to cylindrical inclusion, nuclear inclusion and helper component proteins. Virology124, 434-444

Hellmann, G. M., Chu, L.-Y., and Rhoads, R. E. (1982) A polypeptide which reverses cap analogue inhibition of cell-free protein synthesis. Purification and binding of capped oligonucleotides. J. Biol. Chem. 257, 4056-4062

Munns, T. W., Liszewski, M. K., Tellum, J. T., Sims, H. F., and Rhoads, R. E. (1982) Antibody-nucleic acid complexes. Immunospecific retention of globin mRNA with antibodies specific for 7-methylguanosine. Biochemistry21, 2922-2928

Malek, L. T., Eschenfeldt, W. H., Munns, T. W., and Rhoads, R. E. (1981) Heterogeneity of the 5'-terminus of ovalbumin messenger ribonucleic acid. Nucl. AcidsRes. 9, 1657-1673

Hellmann, G. M., Shaw, J. G., Lesnaw, J. A., Chu, L.-Y., Pirone, T. P., and Rhoads, R. E. (1980) Cell-free translation of tobacco vein mottling virus RNA. Virology106, 207-216

Chu, L.-Y., and Rhoads, R. E. (1980) Inhibition of cell-free messenger ribonucleic acid translation by 7-methylguanosine 5'-triphosphate: Effect of messenger ribonucleic acid concentration. Biochemistry19, 184-191

Malek, L. T., Breter, H.-J., Hellmann, G. M., Friderici, K. H., Rottman, F. M., and Rhoads, R. E. (1979) 5'-terminal structure of hen ovalbumin messenger ribonucleic acid. J. Biol. Chem. 254,

Breter, H.J., Malek, L.T., Hellmann, G.M., and Rhoads, R.E. (1979) Determination of 7-methylguanosine-containing 5'-termini of messenger ribonucleic acid by NaB[ 3H] 4 labeling and high performance liquid anion-exchange chromatography. Anal. Biochem. 98, 102-111

Chu, L.-Y., Lockard, R. E., RajBhandary, U. L., and Rhoads, R. E. (1978) Paradoxical observations on the 5'-terminus of ovalbumin messenger ribonucleic acid. J. Biol. Chem. 253, 5228-5231

Chu, L.-Y., and Rhoads, R. E. (1978) Translational recognition of the 5'-terminal 7-methylguanosine of globin messenger RNA as a function of ionic strength. Biochemistry17, 2450-2455

Rhoads, R. E., and Hellmann, G. M. (1978) Chromatography of ovalbumin messenger ribonucleic acid on complementary deoxyribonucleic acid-cellulose. J. Biol. Chem. 253, 1687-1693

Rhoads, R. E. (1975) Ovalbumin messenger ribonucleic acid. Purification and fractionation on the basis of polyadenylate content by thermal elution from oligodeoxythymidylate-cellulose. J. Biol. Chem. 250, 8088-8097

Rhoads, R. E., McKnight, G. S., and Schimke, R. T. (1973) Quantitative measurement of ovalbumin messenger ribonucleic acid activity: Localization in polysomes, induction by estrogen, and effect of actinomycin D. J. Biol. Chem. 248, 2031-2039

Rhoads, R. E., McKnight, G. S., and Schimke, R. T. (1971) Synthesis of ovalbumin in a rabbit reticulocyte cell-free system programmed with hen oviduct ribonucleic acid. J. Biol. Chem. 246, 7407-7410

Cardinale, G. J., Rhoads, R. E., and Udenfriend, S. (1971) Simultaneous incorporation of 180 into succinate and hydroxyproline catalyzed by collagen proline hydroxylase. Biochem. Biophys. Res. Comm. 43, 537-543

McGee, J. O., Rhoads, R. E., and Udenfriend, S. (1971) The substrate recognition site of collagen proline hydroxylase: The hydroxylation of X-Pro-Gly sequences in bradykinin analogs and other peptides. Arch. Biochem. Biophys. 144, 343-351

Rhoads, R. E., Udenfriend, S., and Bornstein, P. (1971) Invitro enzymatic hydroxylation of prolyl residues in the a1-CB2 fragment of rat collagen. J. Biol. Chem. 246, 4138-4142

Rhoads, R. E., and Udenfriend, S. (1970) Purification and properties of collagen proline hydroxylase from newborn rat skin. Arch. Biochem. Biophys. 139, 329-339

Rhoads, R. E., and Udenfriend, S. (1969) Substrate specificity of collagen proline hydroxylase:Hydroxylation of a specific proline residue in bradykinin. Arch. Biochem. Biophys. 133, 108-111

Rhoads, R. E., and Udenfriend, S. (1968) Decarboxylation of a-ketoglutarate coupled to collagen proline hydroxylase. Proc. Acad. Natl. Acad. Sci. USA60, 1473-1478

Rhoads, R. E., Hutton, J. J., and Udenfriend, S. (1967) Factors which stimulate collagen proline hydroxylase. Arch. Biochem. Biophys. 122, 805-807

Invited Book Chapters, Review Articles, Symposium Proceedings, and Edited Books

Rhoads, R. E., (2004) Translational Control and the Cell Cycle, in Stein, G. S., and Pardee, A. B. (eds), Cell Cycle and Growth Control: Biological Regulation and Cancer, second edition, Wiley and Sons, Inc.

Jemielity, J., Zuberek, J., Stepinski, J., Lewdorowicz, M., Niedzwiecka, A., Haber, D., Fowler, T., Stolarski, R., Rhoads, R. E., and Darzynkiewicz, E. (2002) Synthesis, physio-chemical and biochemical properties of the novel tri-, tetra- and pentaphosphate mRNA cap analogues, in Tocik, Z., and Hocek, M. (eds.) Chemistry of Nucleic Acid Components, Collection Symposium Series, Vol. 5, pp. 159-168, Acad. Sci. Czech Repub., Prague

Mendez, R., Welsh, G., Kleijn, M., Myers M. G., White, M. F., Proud, C. G., and. Rhoads, R. E. (2001) Regulation of protein synthesis by insulin through IRS-1, in Rhoads (ed) Prog. Nucl. Acids Res. and Mol. Biol.26, Springer-Verlag, Berlin, pp. 49-93

Rhoads, R. E. (ed.) Signaling Pathways for Translation. Stress, Calcium and Rapamycin. Prog. Nucl. Acids Res. and Mol. Biol. 27, Springer-Verlag, Berlin (2001)

Rhoads, R. E. (ed.) Signaling Pathways for Translation. Insulin and Nutrients. Prog. Nucl. Acids Res. and Mol. Biol. 26, Springer-Verlag, Berlin (2001)

Niedzwiecka-Kornas, A., Chlebicka, L., Stepinski, J., Jankowska-Anyszka, M., Wieczorek, Z., Darzynkiewicz, E., Rhoads, R. E., and Stolarski, R. (1999) Spectroscopic studies on association of mRNA cap-analogues with human translation factor eIF4E. From modelling of interactions to inhibitory properties, in Holy, A., and Hocek, M. (eds.) Chemistry of Nucleic Acid Components, Collection Symposium Series, Vol. 2, pp. 214-218, Acad. Sci. Czech Repub., Prague

Rhoads, R. E. (1999) Minireview: Signal transduction pathways that regulate eukaryotic protein synthesis, J. Biol. Chem.274,

Keiper, B. D., Gan, W., and Rhoads, R. E. (1999) Molecules in focus: Protein synthesis initiation factor 4G, Int. J. Biochem. Cell Biol.31, 37-41

Clark, B. F. C., Grunberg-Manago, M., Gupta, N. K., Hershey, J. W. B., Hinnebusch, A. G., Jackson, R. J., Maitra, U., Merrick, W. C., Rhoads, R. E., Sonenberg, N., Spremulli, L. L., Trachsel, H., and Voorma, H. O. (1996) Prokaryotic and eukaryotic translation factors, Biochemie 78, 1119-1122

Rhoads, R. E., and Lamphear, B. J. (1995) Cap-independent translation of heat shock messenger RNAs, in Sarnow, P. (ed.), Cap-Independent Translation, Current Topics in Microbiology and Immunology203, 131-153, Springer-Verlag, Berlin

Rhoads, R. E., Joshi, B., and Minich, W. B. (1994) Participation of initiation factors in the recruitment of mRNA to ribosomes. Biochimie76, 831-838 (This issue honors the career of Ed Henshaw.)

Rhoads, R. E., Joshi-Barve, S., and Rinker-Schaeffer, C. (1993) Mechanism of action and regulation of protein synthesis initiation factor 4E. Effects on mRNA discrimination, cellular growth rate, and oncogenesis. Prog. Nucl. Acids Res. and Mol. Biol. 46, 183-219

Rhoads, R. E. (1993) Minireview: Regulation of eukaryotic protein synthesis by initiation factors. J. Biol. Chem. 268, 3017-3020

Rhoads, R. E. (1991) Protein synthesis, cell growth and oncogenesis, in Current Opinion in Cell Biology3, 1019-1024

Shaw, J. G., Hunt, A. G., Pirone, T. P., and Rhoads, R. E. (1990) Organization and expression of potyvirus genes, in T. P. Pirone and J.G. Shaw (eds.) Viral Genes and Plant Pathogenesis, pp. 107-123, Springer-Verlag, New York

Rhoads, R. E. (1991) Chapter 5: Initiation: mRNA and 60S Subunit Binding, in H. Trachsel (ed.) Translation in Eukaryotes, pp. 109-148, CRC Press, Inc., Boca Raton, FL

Rhoads, R. E. (1988) Cap recognition and the entry of mRNA into the protein synthesis initiation cycle. TrendsBiochem. Sci. 13, 52-56

Lesnaw, J. A., Byrd, A., Lacy, L., Hellmann, G., and Rhoads, R. E. (1987) The New Jersey serotype of VSV synthesizes two hypomethylated cap structures in vitro, in B. W. Mahy and D. Kolakofsky (eds.) The Biology of Negative Strand Viruses, pp. 175-182, Elsevier Science Publishers BV (Biomedical Division), Amsterdam

Brandt, P., Zurini, M., Sisken, B. F., Rhoads, R. E., and Vanaman, T. C. (1987) Structural studies, molecular cloning, and localization of the plasma membrane Ca 2+ pumping ATPase, in A. N. Norman, A. R. Means, and T. C. Vanaman (eds.) Calcium Binding Proteins - 1986, Academic Press, Inc., New York, NY

Jones, G., Hiremath, S., Hellmann, G., Wozniak, M., and Rhoads, R. E. (1987) Stimulatory and inhibitory control of developmentally regulated hemolymph proteins in Trichoplusiani, in J. Law (ed.) MolecularEntomology, UCLA Symposium on Molecular and Cellular Biology, New Series, 49, Alan R. Liss, Inc., New York, NY, pp. 295-304

Rhoads, R. E., Hiremath, L. S., Rychlik, W., Gardner, P. R., and Morgan, J. L. (1985) The messenger RNA cap-binding protein, in E.A. Smuckler and G.A. Clawson (eds.) Nuclear Envelope Structure and RNA Maturation, UCLA Symposium on Molecular and Cellular Biology, New Series, 26, Alan R. Liss, Inc., New York, NY

Rhoads, R. E. (1985) The cap structure of eukaryotic messenger RNA and its interaction with cap-binding protein, in F.E. Hahn, D.J. Kopecko, and W.E.G. Muller (eds.) Prog. Nucl. Acids Res. and Mol. Biol.9, Springer-Verlag, Berlin, pp. 104-155

Schimke, R. T., Rhoads, R. E., and McKnight, G. S. (1974) Assay of ovalbumin mRNA in reticulocyte lysate, Methods in Enzymology30, 694-701

Schimke, R. T., Palmiter, R. D., Palacios, R., Rhoads, R. E. (1973) McKnight, S., Sullivan, D., and Summers, M., Estrogen regulation of ovalbumin mRNA content and utilization, in Ruddle, F. H. (ed.) Genetic Mechanisms of Development, Academic Press, New York, pp. 225-249

Schimke, R. T., Rhoads, R. E., Palacios, R., and Sullivan, D. (1973) Ovalbumin mRNA, complimentary DNA, and hormone regulation in chick oviduct, in Niu, M. C., and Segal, S. J. (eds.), The Role of RNA in Reproduction and Development, North-Holland Publishing Co., Amsterdam, pp. 26-42

Schimke, R. T., Palacios, R., Palmiter, R. D., and Rhoads, R. E. (1972) Hormonal regulation of ovalbumin synthesis in chick oviduct, in Kenney, F. T., Hamkalo, B. A., Favelukes, G., and August, J. T. (eds.) Gene Expression and Its Regulation, Plenum Publishing Corp., New York, pp. 123-135

Rhoads, R. E., Roberts, N., and Udenfriend, S. (1971) Collagen proline hydroxylase. Methodsin Enzymology17B, 306-316