Department of Biochemistry and Molecular Biology

Department of Biochemistry and Molecular Biology

The Biochemistry department, located on the 7th floors of the medical school building and the Biomedical Research Institute (BRI), maintains shared instrumentation essential for biochemistry and molecular biology research. A walk-in cold room and a darkroom with automatic X-ray film developer are located in the medical school building.  Autoclaves are located both in the medical school building and the BRI. In addition to other basic required instruments, the department maintains two gel documentation systems, UV irradiator, Storm PhosphorImager, BiaCore protein interaction detection instrument, a stopped-flow spectrofluorometer, and a steady-state and lifetime spectrofluorometer in common equipment rooms. The department also maintains two shared cell culture facilities. 

Feist-Weiller Cancer Center/ Department of Biochemistry and Molecular Biology Center for Experimental Cancer Therapeutics (CECAT)

CECAT maintains equipment and resources for high throughput drug screening using in vitro or cell-based assays, including a Cellomics ArrayScan VTI HCS Reader. Most importantly, the core maintains compound libraries including a library of 1,200 compounds from Prestwick chemical, the NIH Clinical Collection of 450 drugs previously tested in clinical trials, and a proprietary library of over 400 compounds that have validated anti-inflammatory efficacy that are being explored for their anti-tumor efficacy. Additionally, the GreenPharma library composed of 250 natural compounds, as well as the ChemDiv 628otp01 10,000 compound diversity library are available.